The Digital Systems and Media Computing Laboratory (DSMC) was established in the end of 2002 and is located in Patras, Greece. DSMC operates under the School of Sciences and Technology of the Hellenic Open University (HOU) the only University in Greece offering open and distance learning. DSMC’s main objectives are to conduct internationally competitive research and deliver high quality teaching. DSMC conducts both fundamental and applied research in the fields of embedded networked system design, Internet of Things and smart systems, edge cloud networks, digital system design, image and video compression, data hiding and watermarking techniques and has been involved in several European and National research projects. Recently DSMC has been involved as Scientific Coordinator of H2020 project EMYNOS and Greek NSRF 2014 – 2020 project MANTIS. DSMC has also developed the only open, remotely accessible laboratory through a web-interface in Greece and offers a series of courses sponsored by several parties (IEEE CAS society, Altera/Intel, Google) focusing mainly on under-graduate and graduate students following physical and engineering sciences.